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Source: Autumn view of Slioch from Grudie, Loch Maree, A

Forestry Tags > Tag based links for Chimera

The following links have been tagged chimera by users just like you, because these resources are off-site we cannot guarantee the accuracy or quality of any third-party information.

A C-terminal segment of the V(1)R vasopressin receptor is unstructured in the crystal structure of its chimera with the maltose-bindin g protein.: Acta Crystallograph Sect F Struct Biol Cryst Commun, Vol. 61, No. Pt 4. (1 April 2005), pp. 341-345.The V(1) vascular vasopressin receptor (V(1)R) is a G-protein-coup led receptor (GPCR) involved in the regulation of body-fluid osmolality, blood volume and blood pressure. Signal transduction is mediated by the third intracellular loop of this seven-transmem brane protein as well as by the C-terminal cytoplasmic segment. A chimera of the maltose-bindin g protein (MBP) and the C-terminal segment of V(1)R has been cloned, expressed, purified and crystallized. The crystals belong to space group P2(1), with unit-cell parameters a = 51.10, b = 66.56, c = 115.72 A, beta = 95.99 degrees . The 1.8 A crystal structure reveals the conformation of MBP and part of the linker region of this chimera, with the C-terminal segment being unstructured. This may reflect a conformational plasticity in the C-terminal segment that may be necessary for proper function of V(1)R.

Source: Acta Crystallograph Sect F Struct Biol Cryst Commun, Vol. 61, No. Pt 4. (1 April 2005), pp. 341-345.
Synaptic code for sensory modalities revealed by C. elegans GLR-1 glutamate receptor.: Nature, Vol. 378 (1995), pp. 82-85.How does the nervous system encode environmental stimuli as sensory experiences? Both the type (visual, olfactory, gustatory, mechanical or auditory) and the quality of a stimulus (spatial position, intensity or frequency) are represented as a neural code. Here we undertake a genetic analysis of sensory modality coding in Caenorhabditis elegans. The ASH sensory neurons respond to two distinct sensory stimuli (nose touch and osmotic stimuli). A mutation in the glr-1 (glutamate receptor) gene eliminates the response to nose touch but not to osmotic repellents. The predicted GLR-1 protein is roughly 40% identical to mammalian AMPA-class glutamate receptor (GluR) subunits. Analysis of glr-1 expression and genetic mosaics indicates that GLR-1 receptors act in synaptic targets of the ASH neurons. We propose that discrimination between the ASH sensory modalities arises from differential release of ASH neurotransmitt ers in response to different stimuli.

Source: Nature, Vol. 378 (1995), pp. 82-85.
A survey of data provenance in e-science: SIGMOD Rec., Vol. 34, No. 3. (September 2005), pp. 31-36.

Source: SIGMOD Rec., Vol. 34, No. 3. (September 2005), pp. 31-36.
UCSF Chimera--a visualization system for exploratory research and analysis.: J Comput Chem, Vol. 25, No. 13. (October 2004), pp. 1605-1612.The design, implementation , and capabilities of an extensible visualization system, UCSF Chimera, are discussed. Chimera is segmented into a core that provides basic services and visualization, and extensions that provide most higher level functionality. This architecture ensures that the extension mechanism satisfies the demands of outside developers who wish to incorporate new features. Two unusual extensions are presented: Multiscale, which adds the ability to visualize large-scale molecular assemblies such as viral coats, and Collaboratory, which allows researchers to share a Chimera session interactively despite being at separate locales. Other extensions include Multalign Viewer, for showing multiple sequence alignments and associated structures; ViewDock, for screening docked ligand orientations; Movie, for replaying molecular dynamics trajectories; and Volume Viewer, for display and analysis of volumetric data. A discussion of the usage of Chimera in real-world situations is given, along with anticipated future directions. Chimera includes full user documentation, is free to academic and nonprofit users, and is available for Microsoft Windows, Linux, Apple Mac OS X, SGI IRIX, and HP Tru64 Unix from http://www.cgl .ucsf.edu/chim era/.

Source: J Comput Chem, Vol. 25, No. 13. (October 2004), pp. 1605-1612.
Generating mice with targeted mutations: Nat Med, Vol. 7, No. 10. (October 2001), pp. 1086-1090.

Source: Nat Med, Vol. 7, No. 10. (October 2001), pp. 1086-1090.
Evidence of a chimeric genome in the cyanobacterial ancestor of plastids: BMC Evolutionary Biology, Vol. 8 (23 April 2008), 117.

Source: BMC Evolutionary Biology, Vol. 8 (23 April 2008), 117.
Applying Chimera Virtual Data Concepts to Cluster Finding in the Sloan Sky Survey: sc, Vol. 00 (2002)In many scientific disciplines ? especially long running, data- intensive collaborations ? it is important to track all aspects of data capture, production, transformation , and analysis. In principle, one can then audit, validate, reproduce, and/or re-run with corrections various data transformation s. We have recently proposed and prototyped the Chimera virtual data system, a new database-drive n approach to this problem. We present here a major application study in which we apply Chimera to a challenging data analysis problem: the identification of galaxy clusters within the Sloan Digital Sky Survey. We describe the problem, its computational procedures, and the use of Chimera to plan and orchestrate the workflow of thousands of tasks on a data grid comprising hundreds of computers. This experience suggests that a general set of tools can indeed enhance the accuracy and productivity of scientific data reduction and that further development and application of this paradigm will offer great value.

Source: sc, Vol. 00 (2002)
Mosaic/chimera s and twinning in the current reproductive genetics perspective: Hum. Reprod., Vol. 21, No. 9. (1 September 2006), pp. 2458-2460.10.1 093/humrep/del 294

Source: Hum. Reprod., Vol. 21, No. 9. (1 September 2006), pp. 2458-2460.
Bellerophon: a program to detect chimeric sequences in multiple sequence alignments.: Bioinformatics (Oxford, England), Vol. 20, No. 14. (22 September 2004), pp. 2317-2319.SUMM ARY: Bellerophon is a program for detecting chimeric sequences in multiple sequence datasets by an adaption of partial treeing analysis. Bellerophon was specifically developed to detect 16S rRNA gene chimeras in PCR-clone libraries of environmental samples but can be applied to other nucleotide sequence alignments. AVAILABILITY: Bellerophon is available as an interactive web server at http://foo.mat hs.uq.edu.au/~ huber/bellerop hon.pl

Source: Bioinformatics (Oxford, England), Vol. 20, No. 14. (22 September 2004), pp. 2317-2319.
Chimeric retrogenes suggest a role for the nucleolus in LINE amplification.: FEBS Lett, Vol. 581, No. 16. (26 June 2007), pp. 2877-2882.Chim eric retrogenes, found in mammalian and fungal genomes, are bipartite elements composed of DNA copies of cellular transcripts either directly fused to each other or fused to the 3' part of a LINE retrotransposo n. These cellular transcripts correspond to messenger RNAs, ribosomal RNAs, small nuclear RNAs and 7SL RNA. The chimeras are likely formed by RNA template switches during reverse transcription of LINE elements by their retrotransposi tional machinery. The 5' part of chimeras are copies of nucleolar RNAs, suggesting that the nucleolus plays a significant role in LINE retrotransposi tion. RNAs from the nucleolus might have protective function against retroelement invasion or, alternatively, the nucleolus may be required for retrotransposi tional complex assembly and maturation. These hypotheses will be discussed in this review.

Source: FEBS Lett, Vol. 581, No. 16. (26 June 2007), pp. 2877-2882.

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